In 2013, David Sinclair from Harvard found that older mice had relatively lower levels of NAD+ than younger mice. In the experiment, he added NMN to the water of aged mice, and after just one week, he found that the number and density of their microfilament blood vessels returned to the level of young mice, and even the sample tissue of the two mice could not be seen. There is a clear difference. The muscle blood flow of the aged mice also increased significantly, and what is even more remarkable is that their physical fitness increased by 60% to 80%, and they could run 1,400 feet continuously on the treadmill. Compared with the mice that did not take NMN, they only Able to run 780 feet. Among them, NMN prolongs the cell aging cycle by supplementing NAD+, provides energy for cell mitochondria, and provides fuel for longevity gene sirtuin, which in turn helps repair and maintain cell health.